toxtutor.nlm.nih.govToxTutor - Welcome

 -- Help Resize Text: A- A+ ToxTutor -- Welcome to ToxTutor Introduction ToxTutor is a self-paced tutorial covering key principles of toxicology for users of the National Library of Medicine (NLM) chemical and toxicology databases. While a knowledge of anatomy and physiology is not required for viewing ToxTutor, the Introduction to the Human Body from the National Cancer Institute provides a good introduction to the topic. What's New in ToxTutor? August 2018 Release Continuing Education / Certificate of Completion This course is approved for 3 contact hours for California Registered Environmental Health Specialists (REHSs) and National Environmental Health Association's (NEHA) REHS/RSs. To take the tutorial and receive a certificate, please register and complete the tutorial through our free learning management system. × What's New in ToxTutor (August 2018 release)? In Section 3 (Toxic Effects): Added the new topic of "The Microbiome" after the Metabolism content In Section 5 (Toxicity Testing Methods): Did a change in the title of the "Future Approaches and Methods" to "Emerging Approaches and Methods." Added additional content in "Finding Information about Alternatives to Animal Testing." Added Microphysiological Systems as used in "tissue chip" and "Organs-on-chips" models. Added "Human-on-a-Chip" content. Added Induced Pluripotent Stem Cells (iPSCs) as an emerging approach. Added the topic of combining "chips" and iPSCs. In Section 6 (Risk Assessment): Added more content on Adverse Outcome Pathways (AOPs). Added the new topic of "What to Consider when Reading about a New Exposure Study." In Section 7 (Exposure Standards and Guidelines): Added the new topic of Food Safety in the European Union. Added a new section on Intuitive Toxicology, and Risk Communication (including content on Uncertainty). Added a new Section on Environmental Toxicology (with the examples of Microplastics and the Health of Bees as global issues), Environmental Health, and One Health. Close Topics Covered in this Course ToxTutor is divided into the following sections: Introduction to Toxicology Dose and Dose Response Toxic Effects Interactions Toxicity Testing Methods Risk Assessment Exposure Standards and Guidelines Basic Physiology Introduction to Toxicokinetics Absorption Distribution Biotransformation Excretion Cellular Toxicology Intuitive Toxicology and Risk Communication Environmental Toxicology, Environmental Health, and One Health Conclusion Each section of ToxTutor contains one or more related content pages. Next and Back buttons are provided to allow you to navigate through these pages. For more information, see the "Getting Around" section below. The basic principles of toxicology described in ToxTutor are similar to those taught in university programs and are well described in toxicology literature. A list of the textbooks used as the primary resources for the tutorials is found in the Bibliography . Using ToxTutor Getting Around It will take approximately three hours to complete this self-paced tutorial. There are a variety of ways you can navigate ToxTutor. You can: Use the Menu button in the upper right corner of each page to access the main sections, view the glossary or bibliography, or contact support. Click the links in the list above to access sections directly. Click the Back and Next buttons at the bottom of each page to move through the material. Press the left and right arrow keys on your keyboard to move through the material. Use a combination of the above methods to explore the course contents. Progress At the top of each page in ToxTutor are links indicating where the current page falls within the overall ToxTutor program. You can click these links to return to this homepage or to the section that contains the page. Links Throughout the course, you will encounter links. Any link with an External Link icon ( ) points to a resource outside of ToxTutor, which will typically open in a new tab or window. All other links are to other areas within ToxTutor. In many cases, a link will open a small pop-up box within the page to provide more information. In addition, clicking on an image will open a larger view of it in a pop-up box within the page. Getting Help If you need help using ToxTutor or have questions or comments about any of the content presented here, please select the About ToxTutor/Getting Help option from the upper-right menu. × Small pop-up box This is an example of a pop-up within ToxTutor. These are included throughout the course to provide additional information or resources related to a particular topic. You can close these pop-ups by: Clicking the Close button Clicking the X in the upper right corner of the pop-up Pressing ESC on your keyboard Clicking anywhere on the page outside the pop-up Close ← Back Next → --...